EAAT2 Recombinant Antibody, AbBy Fluor™ 594 Conjugated
Product Specifications
Background
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
Synonyms
Excitatory amino acid transporter 2; Excitotoxic amino acid transporter 2; Glial high affinity glutamate transporter; GLT 1; GLT1; Glutamate aspartate transporter II; SLC1A2; Sodium dependent glutamate aspartate transporter 2; Solute carrier family 1 glial high affinity glutamate transporter member 2; Solute carrier family 1 member 2; Excitatory amino acid transporter 2; GLT-1; SLC1A2; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2.
Gene ID
6506
Swiss Prot
P43004
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Target
EAAT2
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 594
Source
KLH conjugated synthetic peptide derived from human EAAT2
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
590nm/617nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6506
Predicted Cross Reactivity
Human
Available Sizes
Curated Selection
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