RNAIII-inhibiting peptide (TFA)

RNAIII-inhibiting peptide (TFA) is a potent inhibitor of Staphylococcus aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis.

Product Specifications

CAS Number

[2703745-76-8]

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/RNAIII-inhibiting_peptide_TFA_.html

Purity

99.66

Solubility

DMSO : ≥ 150 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

FC(F)(F)C(O)=O.O=C(N[C@@H](CO)C(N1[C@@H](CCC1)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=C(C=C5)O)N

Molecular Formula

C47H57F3N10O13

Molecular Weight

1027.01

References & Citations

[1]Gov Y, et al. RNAIII inhibiting peptide (RIP), a global inhibitor of Staphylococcus aureus pathogenesis: structure and function analysis. Peptides. 2001 Oct;22 (10) :1609-20.|[2]Giacometti A, et al. RNAIII-inhibiting peptide improves efficacy of clinically used antibiotics in a murine model of staphylococcal sepsis. Peptides. 2005 Feb;26 (2) :169-75.