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CD134 Recombinant Antibody, RBITC Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008].

Synonyms

CD134 / OX40L receptor; Tumor necrosis factor receptor superfamily member 4; TNFRSF4; ACT 35; ACT35; ACT35 antigen; CD 134; CD134 antigen; Lymphoid activation antigene ACT35; OX 40; OX40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally activated glycoprotein 1 receptor; TNFRSF 4; TNR4_HUMAN.

Gene ID

7293

Swiss Prot

P43489

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

CD134

Clonality

Recombinant

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human CD134

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

Lot dependent

Dilution

WB (IHC-P (1:200-500) ), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7293

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