IRF3 Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].
Synonyms
Interferon regulatory factor 3; IRF-3; IRF 3; IRF3_HUMAN.
Gene ID
3661
Swiss Prot
Q14653
Cellular Locus
Cytoplasm, Nucleus
Host
Mouse
Cross Reactivity
Human
Target
IRF3
Clonality
Monoclonal
Isotype
IgG
Clone
5G9
Conjugation
Unconjugated
Source
Recombinant protein of human IRF3
Applications
IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
3661
Curated Selection
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