Arylomycin A2

Arylomycin A2, an antibiotic (Antibiotic), is a lipopeptide type I signal peptidase (SPase I) inhibitor. Arylomycin A2 has antibacterial effects[1].

Product Specifications

CAS Number

[459844-20-3]

UNSPSC

12352209

Target

Antibiotic; Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/arylomycin-a2.html

Purity

97.37

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1NC([C@H](C)NC([C@@H](N(C)C(CNC([C@@H](C)NC([C@@H](CO)N(C)C(CCCCCCCCC(C)C)=O)=O)=O)=O)C2=CC=C(C(C3=CC(C1)=CC=C3O)=C2)O)=O)=O)O

Molecular Formula

C42H60N6O11

Molecular Weight

824.96

References & Citations

[1]Mark Paetzel, et al. Crystallographic and biophysical analysis of a bacterial signal peptidase in complex with a lipopeptide-based inhibitor. J Biol Chem. 2004 Jul 16;279 (29) :30781-90. |[2]Katrijn Bockstael, et al. Evaluation of the type I signal peptidase as antibacterial target for biofilm-associated infections of Staphylococcus epidermidis. Microbiology (Reading) . 2009 Nov;155 (Pt 11) :3719-3729.