DBF4 Monoclonal Antibody
Product Specifications
Background
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
Synonyms
Activator of S phase kinase antibody, ASK antibody, CHIF antibody, Chiffon homolog A antibody, DBF4 antibody, DBF4 homolog (S. cerevisiae) antibody, DBF4 homolog antibody, DBF4 type zinc finger containing protein 1 antibody, DBF4 zinc finger A antibody, DBF4 zinc finger antibody, DBF4, S. cerevisiae, homolog of antibody, DBF4-type zinc finger-containing protein 1 antibody, DBF4A antibody, DBF4A_HUMAN antibody, Dumbbell former 4, S. cerevisiae, homolog of antibody, OTTHUMP00000161661 antibody, Protein DBF4 homolog A antibody, ZDBF1 antibody, Zinc finger, DBF-type containing 1 antibody
Gene ID
10926
Swiss Prot
Q9UBU7
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
DBF4
Clonality
Monoclonal
Isotype
IgG
Clone
5H0
Conjugation
Unconjugated
Source
Synthetic Peptide within N-terminal human DBF4.
Applications
WB, FCM
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
10926
Curated Selection
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