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Phospho-GluR1 (S845) Monoclonal Antibody

Product Specifications

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Synonyms

GLUR 1 antibody, GLUR A antibody, AMPA 1 antibody, AMPA selective glutamate receptor 1 antibody, AMPA-selective glutamate receptor 1 antibody, GluA1 antibody, GLUH1 antibody, GluR K1 antibody, GluR-1 antibody, GluR-A antibody, GluR-K1 antibody, GLUR1 antibody, GLURA antibody, GluRK1 antibody, Glutamate receptor 1 antibody, Glutamate receptor ionotropic AMPA 1 antibody, Glutamate receptor ionotropic antibody, Glutamate receptor, ionotropic, AMPA 1 antibody, Gria1 antibody, GRIA1_HUMAN antibody, HBGR1 antibody, MGC133252 antibody, OTTHUMP00000160643 antibody, OTTHUMP00000165781 antibody, OTTHUMP00000224241 antibody, OTTHUMP00000224242 antibody, OTTHUMP00000224243 antibody

Gene ID

2890

Swiss Prot

P42261

Modification Site

Ser845

Cellular Locus

Cell membrane, Cell junction, Cell projection, Endoplasmic reticulum membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-GluR1 (S845)

Clonality

Monoclonal

Isotype

IgG

Clone

6E9

Conjugation

Unconjugated

Source

Synthetic phospho-Peptide corresponding to residues surrounding Ser845 of human GluR1.

Applications

WB, FCM

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

2890

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