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RPA32/RPA2 (phospho T21) Monoclonal Antibody

Product Specifications

Background

Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Functions as component of the alternative replication protein A complex (aRPA) . aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Synonyms

60S acidic ribosomal protein P1 antibody, AA409079 antibody, AI325195 antibody, AU020965 antibody, ik:tdsubc_2g1 antibody, M (2) 21C antibody, MGC137236 antibody, OTTHUMP00000004008 antibody, p32 antibody, p34 antibody, RCJMB04_6d17 replication protein A2, 32kDa antibody, REPA2 antibody, Replication factor A protein 2 antibody, Replication protein A 32 kDa subunit antibody, Replication protein A 32kDa subunit antibody, Replication protein A 34 kDa subunit antibody, Replication protein A antibody, Replication Protein A2 (32kDa) antibody, Replication protein A2 antibody, Replication protein A2, 32kDa antibody, RF-A protein 2 antibody, Rf-A2 antibody, RFA antibody, RFA2_HUMAN antibody, RP-A p32 antibody, RP-A p34 antibody, RP21C antibody, RPA 2 antibody, RPA 32 antibody, RPA antibody, Rpa2 antibody, RPA32 antibody, RPA34 antibody, RpLP1 antibody, RpP2 antibody, xx:tdsubc_2g1 antibody, zgc:109822 antibody

Gene ID

6118

Swiss Prot

P15927

Modification Site

Thr21

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

RPA32/RPA2 (phospho T21)

Clonality

Monoclonal

Isotype

IgG

Clone

13F7

Conjugation

Unconjugated

Source

Recombinant protein

Applications

WB, IP

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IP (1-2ug)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

6118

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