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BRD2 Recombinant Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The bromodomain-containing proteins are ubiquitously expressed. BRD2 may play a role in spermatogenesis or folliculogenesis (By similarity) . BRD2 binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.

Synonyms

Bromodomain-containing protein 2; O27.1.1; Really interesting new gene 3 protein; BRD2; KIAA9001; RING3

Gene ID

6046

Swiss Prot

P25440

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

1-50/801

Target

BRD2

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

Recombinant protein within human BRD2 aa 1-200.

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6046

Available Sizes

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