P2Y6 Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
P2Y6 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene. Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Synonyms
P2Y purinoceptor 6; P2Y6; P2RY6
Gene ID
5031
Swiss Prot
Q15077
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
P2Y6
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
Synthetic peptide corresponding to N-terminal human P2Y6.
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5031
Available Sizes
Curated Selection
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