ENDOG (2C1) Monoclonal Antibody
Product Specifications
Background
Cleaves DNA at double-stranded (DG) n. (DC) n and at single-stranded (DC) n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
Synonyms
Endonuclease G mitochondrial; Endo G; ENDOG.
Gene ID
2021
Swiss Prot
Q14249
Cellular Locus
Nucleus, Mitochondrion
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
ENDOG
Clonality
Monoclonal
Isotype
IgG
Clone
2C1
Conjugation
Unconjugated
Source
Synthetic peptide of C-terminal human Endo G
Applications
WB, IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
2021
Curated Selection
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