Plexin A1 (2G1) Monoclonal Antibody

Product Specifications

Background

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Synonyms

Plexin-A1; Semaphorin receptor NOV; PLXNA1; NOV; PLXN1

Gene ID

5361

Swiss Prot

Q9UIW2

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

PLXNA1

Clonality

Monoclonal

Isotype

IgG

Clone

2G1

Conjugation

Unconjugated

Source

Recombinant protein within human Plexin A1 aa 1-200

Applications

WB, FCM, IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

5361

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