Plexin A1 (2G1) Monoclonal Antibody
Product Specifications
Background
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
Synonyms
Plexin-A1; Semaphorin receptor NOV; PLXNA1; NOV; PLXN1
Gene ID
5361
Swiss Prot
Q9UIW2
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
PLXNA1
Clonality
Monoclonal
Isotype
IgG
Clone
2G1
Conjugation
Unconjugated
Source
Recombinant protein within human Plexin A1 aa 1-200
Applications
WB, FCM, IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
5361
Curated Selection
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