Trefoil factor 1 Recombinant Antibody, PE-Cy5.5 Conjugated
Product Specifications
Background
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. TFF1 has been found to be a stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. TFF1 may inhibit the growth of calcium oxalate crystals in urine.
Synonyms
Trefoil factor 1; Breast cancer estrogen-inducible protein; PNR-2; Polypeptide P1 A; Protein pS2; hP1 A; BCEI; PS2; TFF1; Estrogen Inducible Protein pS2.
Gene ID
7031
Swiss Prot
P04155
Host
Rabbit
Cross Reactivity
Human
Target
Trefoil factor 1
Clonality
Monoclonal
Isotype
IgG
Clone
4B1
Conjugation
PE-Cy5.5
Source
Synthetic peptide within human TFF1 aa 50-100
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
488nm/694nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
7031
Curated Selection
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