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Trefoil factor 1 Recombinant Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. TFF1 has been found to be a stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. TFF1 may inhibit the growth of calcium oxalate crystals in urine.

Synonyms

Trefoil factor 1; Breast cancer estrogen-inducible protein; PNR-2; Polypeptide P1 A; Protein pS2; hP1 A; BCEI; PS2; TFF1; Estrogen Inducible Protein pS2.

Gene ID

7031

Swiss Prot

P04155

Host

Rabbit

Cross Reactivity

Human

Target

Trefoil factor 1

Clonality

Monoclonal

Isotype

IgG

Clone

4B1

Conjugation

AbBy Fluor™ 680

Source

Synthetic peptide within human TFF1 aa 50-100

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bsm-54139R-BF680

Gene ID URL

7031

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