PPARG coactivator 1 beta (6H5) Monoclonal Antibody
Product Specifications
Background
Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
Synonyms
Peroxisome proliferator-activated receptor gamma coactivator 1-beta; PGC-1-related estrogen receptor alpha coactivator; PGC-1-beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PPARGC1B; PERC; PGC1; PGC1B; PPARGC1.
Gene ID
133522
Swiss Prot
Q86YN6
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Target
PPARGC1B
Clonality
Monoclonal
Isotype
IgG
Clone
6H5
Conjugation
Unconjugated
Source
Recombinant protein within C-terminal human PGC1 beta
Applications
WB, FCM
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
133522
Curated Selection
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