Phospho-MLKL (Ser345) Recombinant Antibody, AbBy Fluor™ 750 Conjugated
Product Specifications
Background
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Synonyms
Phospho-MLKL (S345) ; pMLKL Ser345; Mixed lineage kinase domain-like protein, Mlkl
Gene ID
74568
Swiss Prot
Q9D2Y4
Modification Site
Ser345
Host
Rabbit
Cross Reactivity
Mouse
Target
Phospho-MLKL (Ser345)
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 750
Source
Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
749nm/775nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
74568
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Monoclonal 4-1BB/TNFRSF9/CD137 Antibody (2356B) [Janelia Fluor 646]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
FAB8381J 0.1 mL
Rabbit Monoclonal 4-1BB/TNFRSF9/CD137 Antibody (2356B) [Janelia Fluor 646]
Ask
View Details P9054-61J-ML490 100 µL
PSCA, ID (Prostate Stem Cell Antigen, UNQ206/PRO232) (MaxLight 490) discontinued
Ask
View Details 
MBS7033417-01 0.02 mg
Recombinant Brucella abortus biovar 1 Type IV secretion system protein virB6 (virB6)
Ask
View Details MBS7033417-02 0.1 mg
Recombinant Brucella abortus biovar 1 Type IV secretion system protein virB6 (virB6)
Ask
View Details