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Reelin Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.

Synonyms

Reelin, RELN

Gene ID

5649

Swiss Prot

P78509

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human, Rat

Target

Reelin

Clonality

Monoclonal

Isotype

IgG

Clone

4C3

Conjugation

FITC

Source

Human Reelin aa 241-340

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (WB=1:500-2000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5649

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