Reelin Recombinant Antibody, AbBy Fluor™ 555 Conjugated
Product Specifications
Background
Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
Synonyms
Reelin, RELN
Gene ID
5649
Swiss Prot
P78509
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human, Rat
Target
Reelin
Clonality
Monoclonal
Isotype
IgG
Clone
4C3
Conjugation
AbBy Fluor™ 555
Source
Human Reelin aa 241-340
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
553nm/568nm
Concentration
Lot dependent
Dilution
WB (WB=1:500-2000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5649
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