FFA3 agonist 1

FFA3 agonist 1 is an agonist of free fatty acid receptor 3 (FFA3) . FFA3 agonist 1 regulates the health effect of intestinal microbiota by activating FFA3[1].

Product Specifications

CAS Number

[886358-51-6]

UNSPSC

12352005

Hazard Statement

H315-H319

Target

Free Fatty Acid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ffa3-agonist-1.html

Purity

97.24

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=C(C)NC2=C(C(CCC2)=O)C1C3=CC=CO3)NC4=CC=CC=C4C

Molecular Formula

C22H22N2O3

Molecular Weight

362.42

Precautions

P264-P280-P302+P352-P305+P351+P338-P362+P364

References & Citations

[1]Ulven ER, et al. Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators. J Med Chem. 2020 Apr 9;63 (7) :3577-3595. |[2]Hudson BD, Christiansen E, Murdoch H, Jenkins L, Hansen AH, Madsen O, Ulven T, Milligan G. Complex pharmacology of novel allosteric free fatty acid 3 receptor ligands. Mol Pharmacol. 2014 Aug;86 (2) :200-10.