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H3K36me2 (6C9) Monoclonal Antibody

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene ID

8350

Swiss Prot

P68431

Host

Mouse

Cross Reactivity

Human

Target

H3K36me2

Clonality

Monoclonal

Isotype

IgG1

Clone

6C9

Conjugation

Unconjugated

Source

Monoclonal antibody raised in mouse against histone H3 dimethylated at lysine 36 (H3K36me2), using a KLH-conjugated synthetic peptide

Applications

ELISA, IF (ICC)

Purification

Protein A purified monoclonal antibody in PBS containing 0.05% azide.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

8350

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