ABCG2 Recombinant Antibody, Cy3 Conjugated
Product Specifications
Background
High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.
Synonyms
ATP-binding cassette sub-family G member 2, Breast cancer resistance protein, CDw338, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter, URate exporter, CD_antigen: CD338, ABCG2
Gene ID
9429
Swiss Prot
Q9UNQ0
Host
Rabbit
Cross Reactivity
Human
Target
ABCG2
Clonality
Recombinant
Isotype
IgG
Conjugation
Cy3
Source
Human ABCG2 aa 1-400
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.biossantibodies.com/datasheets/bsm-52821R-Cy3
Gene ID URL
9429
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6291730-01 0.2 mL
DEPD5, CT (DEPDC5, KIAA0645, DEP domain-containing protein 5) (Biotin)
Ask
View Details MBS6291730-02 5x 0.2 mL
DEPD5, CT (DEPDC5, KIAA0645, DEP domain-containing protein 5) (Biotin)
Ask
View Details 
13208141 1x10<sup>6</sup> cells/1.0ml
BCAS2 CRISPR Knock Out 293T Cell Line (Human)
Ask
View Details