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PKC delta Recombinant Antibody, Cy7 Conjugated

Product Specifications

Background

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].

Synonyms

Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, PRKCD

Gene ID

5580

Swiss Prot

Q05655

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PKC delta

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy7

Source

Mouse PKC delta aa 500 to the C-terminus

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

Lot Dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5580

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