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TSG101 Recombinant Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) . Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.

Synonyms

Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101

Gene ID

7251

Swiss Prot

Q99816

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

30-70/390

Target

TSG101

Clonality

Monoclonal

Isotype

IgG

Clone

6C3

Conjugation

AbBy Fluor™ 680

Source

Human TSG101 between 1 to 100 amino acids

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7251

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