TSG101 Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) . Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
Synonyms
Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101
Gene ID
7251
Swiss Prot
Q99816
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
30-70/390
Target
TSG101
Clonality
Monoclonal
Isotype
IgG
Clone
6C3
Conjugation
AbBy Fluor™ 488
Source
Human TSG101 between 1 to 100 amino acids
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
7251
Curated Selection
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