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GRM1 Recombinant Antibody, PerCP Conjugated

Product Specifications

Background

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Synonyms

Glutamate receptor 1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluR-1, GluA1

Gene ID

2890

Swiss Prot

P42261

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

GRM1

Clonality

Monoclonal

Isotype

IgG

Clone

7A9

Conjugation

PerCP

Source

Recombinant protein within Human Glutamate Receptor 1 aa 850 to the C-terminus

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2890

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