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GRM1 Recombinant Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Synonyms

Glutamate receptor 1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluR-1, GluA1

Gene ID

2890

Swiss Prot

P42261

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

GRM1

Clonality

Monoclonal

Isotype

IgG

Clone

7A9

Conjugation

AbBy Fluor™ 405

Source

Recombinant protein within Human Glutamate Receptor 1 aa 850 to the C-terminus

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2890

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