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Hes1 Recombinant Antibody, PerCP Conjugated

Product Specifications

Background

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity) . May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

Synonyms

Transcription factor HES-1, Class B basic helix-loop-helix protein 39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, bHLHb39, hHL, HES1

Gene ID

3280

Swiss Prot

Q14469

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Hes1

Clonality

Recombinant

Isotype

IgG

Conjugation

PerCP

Source

Recombinant human Hes1 between 200 to 300 amino acids

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bsm-52568R-PerCP

Gene ID URL

3280

Available Sizes

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