Caspase-9 Recombinant Antibody, PE-Cy5.5 Conjugated
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) . Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Synonyms
Caspase-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP-9, APAF-3, ICE-LAP6, CASP9
Swiss Prot
P55211
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Caspase-9
Clonality
Recombinant
Isotype
IgG
Conjugation
PE-Cy5.5
Source
Human Caspase-9 aa 200-350
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/694nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15276002 1 Vial
Lentiviral mouse Sik2 shRNA (UAS) - Lentiviral mouse Sik2 shRNA (UAS, iRFP) (25)
Ask
View Details 
A3570-66P1-ML750 100 µL
Arhgef9, ID (Rho Guanine Nucleotide Exchange Factor 9, Rac/Cdc42 Guanine Nucleotide Exchange Factor 9, Collybistin, PEM-2 Homolog, KIAA0424) (MaxLight 750) discontinued
Ask
View Details 
MBS1045056 Inquire
Recombinant Rhodobacter sphaeroides Formate--tetrahydrofolate ligase (fhs), partial
Ask
View Details 