Caspase-9 Recombinant Antibody, FITC Conjugated
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) . Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Synonyms
Caspase-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP-9, APAF-3, ICE-LAP6, CASP9
Swiss Prot
P55211
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Caspase-9
Clonality
Recombinant
Isotype
IgG
Conjugation
FITC
Source
Human Caspase-9 aa 200-350
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Lsx07809-500gEcoli 500 µg (E. coli)
Recombinant Shigella Flexneri gpmB Protein (aa 1-215)
Sign In for Pricing
View Details ![Mouse Monoclonal SOX9 Antibody (SOX9/2398) [Alexa Fluor 350]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NBP3-08399AF350 100 µL
Mouse Monoclonal SOX9 Antibody (SOX9/2398) [Alexa Fluor 350]
Sign In for Pricing
View Details