Caspase-9 Recombinant Antibody, APC Conjugated

Product Specifications

Background

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) . Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Synonyms

Caspase-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP-9, APAF-3, ICE-LAP6, CASP9

Swiss Prot

P55211

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

Caspase-9

Clonality

Recombinant

Isotype

IgG

Conjugation

APC

Source

Human Caspase-9 aa 200-350

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

KN416800 1 Kit

OR2A25 Human Gene Knockout Kit (CRISPR)

Ask

View Details

NBP2-71815MFV500 0.1 mL

Mouse Monoclonal FGF-21 Antibody (OTI2F10) [mFluor Violet 500 SE]

Ask

View Details

NBP2-90259AF647 0.1 mL

Rabbit Monoclonal ABHD14B Antibody (002) [Alexa Fluor 647]

Ask

View Details

E-AB-F1188UC-01 25 µg

FITC Anti-Mouse FcεRIα Antibody[MAR-1]

Ask

View Details

E-AB-F1188UC-02 100 µg

FITC Anti-Mouse FcεRIα Antibody[MAR-1]

Ask

View Details

MBS012327-01 48 Well

Rat Activating Transcription Factor 4 ELISA Kit

Ask

View Details