F11R/JAM-A/CD321 Recombinant Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
Synonyms
Junctional adhesion molecule A; Junctional adhesion molecule 1; Platelet F11 receptor; Platelet adhesion molecule 1; CD321; JAM-A; JAMA; JAM-1; JAM1; PAM-1; F11R
Gene ID
50848
Swiss Prot
Q9Y624
Cellular Locus
Cell membrane, Extracellular domain, Cell junction
Host
Rabbit
Cross Reactivity
Human
Target
F11R/JAM-A/CD321
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy7
Source
Human Junctional Adhesion Molecule 1 between 28-241 amino acids
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
50848
Predicted Cross Reactivity
Mouse, Rat
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