Estrogen Related Receptor alpha (1H13) Monoclonal Antibody
Product Specifications
Background
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.
Synonyms
Steroid hormone receptor ERR1, Estrogen receptor-like 1, Estrogen-related receptor alpha, Nuclear receptor subfamily 3 group B member 1, ERR-alpha, ESRRA, ERR1, ESRL1, NR3B1
Gene ID
2101
Swiss Prot
P11474
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Estrogen Related Receptor alpha
Clonality
Monoclonal
Isotype
IgG
Clone
1H13
Conjugation
Unconjugated
Source
Recombinant protein within Human Estrogen Related Receptor alpha aa 1-100
Applications
WB, FCM
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
2101
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