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NADPH oxidase 4 Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.

Synonyms

NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, Renal NAD (P) H-oxidase, KOX-1, NOX4, RENOX

Gene ID

50507

Swiss Prot

Q9NPH5

Host

Rabbit

Cross Reactivity

Human, Rat

Target

NADPH oxidase 4

Clonality

Monoclonal

Isotype

IgG

Clone

2A4

Conjugation

FITC

Source

Recombinant human NADPH oxidase 4 between 500 to C-terminus

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

50507

Predicted Cross Reactivity

Mouse

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