Bax Recombinant Antibody, AbBy Fluor™ 750 Conjugated

Product Specifications

Background

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Synonyms

Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BCL2L4

Gene ID

581

Swiss Prot

Q07812

Cellular Locus

Cytoplasm, Mitochondrion, Membrane bound

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Bax

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 750

Source

Recombinant human Bak between 20 to 150 amino acids

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

1 mg/ml

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

581

Available Sizes

Curated Selection

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