Bax Recombinant Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Synonyms
Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BCL2L4
Gene ID
581
Swiss Prot
Q07812
Cellular Locus
Cytoplasm, Mitochondrion, Membrane bound
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Bax
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy5.5
Source
Recombinant human Bak between 20 to 150 amino acids
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
1 mg/ml
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
581
Curated Selection
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