Bcl-2 Recombinant Antibody, HRP Conjugated

Product Specifications

Background

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .

Synonyms

Apoptosis regulator Bcl-2; BCL2

Gene ID

596

Swiss Prot

P10415

Cellular Locus

Nucleus, Mitochondrion, Membrane bound, Endoplasmic reticulum

Host

Rabbit

Cross Reactivity

Human

Target

Bcl-2

Clonality

Recombinant

Isotype

IgG

Conjugation

HRP

Source

Recombinant human Bcl-2 between 1 to 200 amino acids.

Applications

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

596

Available Sizes

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