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Histone H3 (mono methyl K36) (6G6) Monoclonal Antibody

Product Specifications

Background

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Synonyms

Histone H3.3, H3f3a

Swiss Prot

P68431

Modification Site

Mono methyl K36

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

Histone H3 (mono methyl K36)

Clonality

Monoclonal

Isotype

IgG

Clone

6G6

Conjugation

Unconjugated

Source

Synthetic peptide surrounding K36 of Histone H3

Applications

WB, IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Methylation

Storage Conditions

Store at -20°C for 12 months.

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