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AX048

AX048 is an inhibitor for calcium-dependent phospholipase A2 cPLA2 with a XI (50) of 0.022 mole fraction and reveals an antihyperalgesic efficacy[1].

Product Specifications

CAS Number

873079-69-7

UNSPSC

12352211

Target

Phospholipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ax048.html

Solubility

10 mM in DMSO

Smiles

O=C(C(CCCCCCCCCCCCCC)=O)NCCCC(OCC)=O

Molecular Formula

C22H41NO4

Molecular Weight

383.57

References & Citations

[1]Yaksh TL, et al., Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release. J Pharmacol Exp Ther. 2006 Jan;316 (1) :466-75.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Phospholipase A

Available Sizes

Frequently Asked Questions

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