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VDAC1 Recombinant Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.

Synonyms

Voltage-dependent anion-selective channel protein 1, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC-1, hVDAC1

Gene ID

7416

Swiss Prot

P21796

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

1-100/283

Target

VDAC1

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy5

Source

Human VDAC1 protein between 1 to 100 amino acids

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bsm-52251R-PE-Cy5

Gene ID URL

7416

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