Stat3 Recombinant Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6) -responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity) .

Synonyms

APRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3

Gene ID

6774

Swiss Prot

P40763

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Stat3

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

Recombinant human Stat3 protein, around N-terminal 1-100aa.

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6774

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

TA502102BM 100 µL

EXDL1 (EXD1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1G1]

View Details

E47M60627 100 µL

CD38 (PE) Recombinant Mouse mAb

View Details

GTR15283537 1 Vial

Lentiviral mouse Fbxo3 shRNA (UAS) - Lentiviral mouse Fbxo3 shRNA (UAS, RFP) plasmid

View Details

MBS7145167 Inquire

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) PLIM2B Polyclonal Antibody

View Details

bsm-33197M-Cy3 100 µL

Pan Methylated Lysine Monoclonal Antibody, Cy3 Conjugated

View Details

E45R26545N-100 100 µL

DIDO1 Rabbit pAb

View Details