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STAT2 Recombinant Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) . Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Synonyms

P113; ISGF-3; STAT113; Signal transducer and activator of transcription 2; STAT2

Gene ID

6773

Swiss Prot

P52630

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

STAT2

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 680

Source

Recombinant human STAT2 protein, around N-terminal 1-100aa.

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6773

Available Sizes

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