Smad2 Recombinant Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Synonyms
JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2; Mothers against decapentaplegic homolog 2; MAD homolog 2; Mothers against DPP homolog 2; Mad-related protein 2; SMAD family member 2; SMAD 2; Smad2
Gene ID
4087
Swiss Prot
Q15796
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Smad2
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy5.5
Source
Recombinant human Smad2 protein, around N-terminal 1-200aa.
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4087
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Polyclonal KIDINS220 Antibody [Alexa Fluor 532]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NBP1-50034AF532 0.1 mL
Rabbit Polyclonal KIDINS220 Antibody [Alexa Fluor 532]
Sign In for Pricing
View Details MBS7154309 Inquire
Rabbit anti-Salmonella typhimurium (strain LT2/SGSC1412/700720) PMRD Polyclonal Antibody
Sign In for Pricing
View Details