PIK3R1 Monoclonal Antibody, Cy5 Conjugated
Product Specifications
Background
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Synonyms
Phosphatidylinositol 3-kinase regulatory subunit alpha; PIK3R1; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PIK3R1; GRB1; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
Gene ID
5295
Swiss Prot
P27986
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Target
PIK3R1
Clonality
Monoclonal
Isotype
IgG1
Clone
9B3
Conjugation
Cy5
Source
Recombinant human PI3-kinase p85 subunit alpha protein, around 600-700aa.
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
625,650nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.biossantibodies.com/datasheets/bsm-52219M-Cy5
Gene ID URL
5295
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7098325 Inquire
Recombinant Myxine glutinosa NADH-ubiquinone oxidoreductase chain 6 (MT-ND6), partial
Ask
View Details 