IRF3 (S386) (28C3) Monoclonal Antibody
Product Specifications
Background
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq].
Synonyms
Bone Morphogenic Protein 6; Decapentaplegic vegetal related; DVR6; BMP 6; BMP-6; TGFB related vegetal related growth factor; Transforming growth factor beta; Vegetal related TGFB related cytokine; Vg related sequence; VGR1; BMP6_HUMAN.
Gene ID
3661
Swiss Prot
Q14653
Modification Site
S386
Host
Rabbit
Cross Reactivity
Human
Target
IRF3 (S386)
Clonality
Monoclonal
Isotype
IgG
Clone
28C3
Conjugation
Unconjugated
Source
Synthetic peptide derived from human IRF3 (S386), around 350-400aa (phospho S386) .
Applications
WB, ICC/IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:500-1000), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
3661
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