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IRF2 Recombinant Antibody, PerCP-Cy5.5 Conjugated

Product Specifications

Background

Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS) ) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.

Synonyms

IRF-2; Interferon regulatory factor 2; IRF2

Gene ID

3660

Swiss Prot

P14316

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

IRF2

Clonality

Recombinant

Isotype

IgG

Conjugation

PerCP-Cy5.5

Source

Recombinant human IRF2 protein, around C-terminal 100aa.

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

482nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3660

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