IRF2 Recombinant Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS) ) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.
Synonyms
IRF-2; Interferon regulatory factor 2; IRF2
Gene ID
3660
Swiss Prot
P14316
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
IRF2
Clonality
Recombinant
Isotype
IgG
Conjugation
PE-Cy7
Source
Recombinant human IRF2 protein, around C-terminal 100aa.
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3660
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