Histone H4 (tri methyl K20) Monoclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Jul 2008].
Synonyms
Histone H4 Acetyl K12; Histone H4 Acetyl Lys12; Acetyl-Histone H4 Lys12; H4F2; H4FN; HIST1H4; HIST2H4; HISTH4H4; methyl histone H4; histone H4; H4_HUMAN.
Gene ID
121504
Swiss Prot
P62805
Modification Site
Tri methyl K20
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Histone H4 (tri methyl K20)
Clonality
Monoclonal
Isotype
IgG
Clone
2C12
Conjugation
AbBy Fluor™ 647
Source
Synthetic peptide derived from human Histone H4 (tri methyl K20), around 1-30aa (tri methyl K20) .
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
Lot Dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Methylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
121504
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