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HIF-1 beta Recombinant Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

Synonyms

HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; ARNT

Gene ID

405

Swiss Prot

P27540

Host

Rabbit

Cross Reactivity

Human

Target

HIF-1 beta

Clonality

Monoclonal

Isotype

IgG

Clone

3F5

Conjugation

AbBy Fluor™ 488

Source

Recombinant human HIF-1 beta protein, around 600-700aa.

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

Lot dependent

Dilution

WB (IHC-P (1:50-200) ), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

405

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