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FOXO3A Monoclonal Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

Synonyms

FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2; Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3

Gene ID

2309

Swiss Prot

O43524

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

FOXO3A

Clonality

Monoclonal

Isotype

IgG

Clone

5G10

Conjugation

AbBy Fluor™ 680

Source

Recombinant human FOXO3A protein, around N-terminal 150aa.

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

Lot Dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2309

Frequently Asked Questions

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